Gall bladder disease can be generated a wide range of unclear clinical manifestations in patients. The patients of gall bladder disease usually experience differentiated signs and symptoms according to their age and sex. Gall bladder formation and problems can occur in both sexes, but the female gender generally experiences more severe and diversified symptoms. The clinical expressions of gall bladder disease are also influenced by the underlying causes of the illness and its stage of progression.

The gall bladder is actually a small organ situated at the close proximity of the liver, in the right upper region of the abdomen. The main purpose of gall bladder is to aid the liver in the process of fat digestion, by collecting and storing bile, then releasing this substance inside the stomach and small intestine when necessary. Formed by the liver, bile pigment has a vital role in the assimilation of vitamins A, D, E and K. The bile actually consists of bile acids, water, phospholipids, electrolytes and bile pigments. Gall bladder disease can be either caused by internal chemical imbalances in the composition of bile which may results in thickening of bile, leading to the formation of gallstones, physiological dysfunctions at the level of the biliary system or gall bladder infections.

In the early stages of the gall stone disease, people with gall bladder affections rarely experience back pain. In the beginning, the gall bladder disease generates symptoms such as indigestion, abdominal bloating, abdominal discomfort, nausea, vomiting and diarrhea. As the gall bladder disease progresses, patients normally experience radiating pain in the region of the right upper abdomen, pain that also eventually moves to the lower back side. Although the lower back pain is not all the time very prominent for gall bladder affections, it is still considered to be an important criterion in the process of diagnosis. Recent studies have shown the fact that the patients of gall bladder disease commonly experience lower back pain in more advanced stages of the illness. This type of indication of gall bladder disease is mostly common in patients with ages over 50, rarely occurring in younger adults or children. Gall bladder back pain can be either the consequence of pronounced inflammation of the gall bladder or biliary colic.

Biliary colic is a common reason of lower back pain. Biliary colic refers to the formation of gall bladder stones inside the gall bladder and hepato-biliary ducts. Biliary calculi actually known as Gallstones and these are small stones formed from excess cholesterol, calcium and bile pigments. When gallstones accrue in large amounts they can obstruct bile ducts completely, facilitating the occurrence of gall bladder infections. This condition associated with gall bladder inflammation and resultant infections, biliary colic generates intense, persistent pain in the region of the lower abdomen and lower back. Gall bladder back pain normally occurs in episodes, each attack lasting from 20-30 minutes to a few hours. The development and accumulation of gallstones at the level of the biliary system is a common ailment, affecting more than 15 percent of people with ages over 50. Gallstones can also easily be observed with the means of ultrasound tests and computerized tomography and patients can be quickly diagnosed with biliary colic.